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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AQP1
All Species:
3.64
Human Site:
T120
Identified Species:
6.67
UniProt:
P29972
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29972
NP_932766.1
269
28526
T120
S
G
I
T
S
S
L
T
G
N
S
L
G
R
N
Chimpanzee
Pan troglodytes
XP_519026
269
28548
N120
S
G
I
T
S
S
L
N
G
N
S
L
G
R
N
Rhesus Macaque
Macaca mulatta
XP_001084411
269
28522
P120
S
G
I
T
S
S
L
P
G
N
S
L
G
R
N
Dog
Lupus familis
XP_543678
271
28842
N119
V
R
G
D
L
A
V
N
A
L
S
N
N
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q02013
269
28775
V120
S
G
I
T
S
S
L
V
D
N
S
L
G
R
N
Rat
Rattus norvegicus
P29975
269
28838
L120
S
G
I
T
S
S
L
L
E
N
S
L
G
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521059
168
18146
G25
V
W
S
F
V
S
W
G
Q
A
L
A
E
G
I
Chicken
Gallus gallus
NP_001034542
270
28478
P121
S
G
V
T
S
S
L
P
Y
N
S
L
G
L
N
Frog
Xenopus laevis
NP_001085391
274
29077
S127
S
G
I
T
T
Q
I
S
K
N
S
L
G
L
N
Zebra Danio
Brachydanio rerio
NP_996942
260
27399
L117
S
K
G
D
A
L
G
L
N
Q
I
H
T
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Z7
245
25557
C102
A
F
Y
I
I
V
Q
C
V
G
A
I
A
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XF58
285
29817
A131
R
A
L
L
Y
I
V
A
Q
C
L
G
A
I
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43286
287
30456
A131
R
A
L
L
Y
I
I
A
Q
C
L
G
A
I
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.1
44.6
N.A.
94
93.3
N.A.
50.9
85.5
74.8
59.4
N.A.
36.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.5
63
N.A.
95.5
95.1
N.A.
58.3
91.8
86.8
75
N.A.
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
6.6
N.A.
86.6
86.6
N.A.
6.6
73.3
60
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
20
N.A.
86.6
86.6
N.A.
6.6
80
80
13.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
39.3
N.A.
41.8
N.A.
N.A.
Protein Similarity:
N.A.
55.4
N.A.
56.1
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
0
8
8
0
16
8
8
8
8
24
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
16
0
0
0
0
16
% C
% Asp:
0
0
0
16
0
0
0
0
8
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
54
16
0
0
0
8
8
24
8
0
16
54
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
47
8
8
16
16
0
0
0
8
8
0
16
16
% I
% Lys:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
16
16
8
8
47
16
0
8
24
54
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
16
8
54
0
8
8
0
54
% N
% Pro:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
0
24
8
0
0
0
0
0
% Q
% Arg:
16
8
0
0
0
0
0
0
0
0
0
0
0
39
0
% R
% Ser:
62
0
8
0
47
54
0
8
0
0
62
0
0
0
0
% S
% Thr:
0
0
0
54
8
0
0
8
0
0
0
0
8
8
8
% T
% Val:
16
0
8
0
8
8
16
8
8
0
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
16
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _